BEERSHEBA, Israel — Israel and Iran exchanged more attacks on Thursday as U.S. President Donald Trump said he would make up his mind within two weeks on whether the U.S. military will get directly involved in the conflict, seeking to keep open the door to diplomacy on Tehran’s nuclear program.

“Based on the fact that there’s a substantial chance of negotiations that may or may not take place with Iran in the near future, I will make my decision whether or not to go within the next two weeks,” Karoline Leavitt, the White House press secretary, told reporters, reading out Trump’s statement.

Trump has been weighing whether to attack Iran by striking its well-defended Fordo uranium enrichment facility, which is buried under a mountain and widely considered to be out of reach of all but America’s “bunker-buster” bombs.

Earlier in the day, Israel’s defense minister threatened Iran’s supreme leader after Iranian missiles crashed into a major hospital in southern Israel and hit residential buildings near Tel Aviv, wounding at least 240 people. As rescuers wheeled patients out of the smoldering hospital, Israeli warplanes launched their latest attack on Iran’s nuclear program.

Israeli Defense Minister Israel Katz blamed Iranian Supreme Leader Ayatollah Ali Khamenei for Thursday’s barrage and said the military “has been instructed and knows that in order to achieve all of its goals, this man absolutely should not continue to exist.”

Prime Minister Benjamin Netanyahu said he trusted that Trump would “do what’s best for America.”

“I can tell you that they’re already helping a lot,” Netanyahu said from the rubble and shattered glass around the Soroka Medical Center in Israel’s southern city of Beersheba.

The open conflict between Israel and Iran erupted last Friday with a surprise wave of Israeli airstrikes targeting nuclear and military sites, top generals and nuclear scientists. At least 639 people, including 263 civilians, have been killed in Iran and more than 1,300 wounded, according to a Washington-based Iranian human rights group.

Iran has retaliated by firing 450 missiles and 1,000 drones at Israel, according to Israeli army estimates. Most have been shot down by Israel’s multitiered air defenses, but at least 24 people in Israel have been killed and hundreds wounded.

Israel’s Home Front Command said one of the Iranian ballistic missiles fired Thursday morning had been rigged with fragmenting cluster munitions. Rather than a conventional warhead, a cluster munition warhead carries dozens of submunitions that can explode on impact, showering small bomblets around a large area and posing major safety risks on the ground. The Israeli military did not say where that missile had been fired.

At least 80 patients and medical workers were wounded in the strike on Israel’s Soroka Medical Center. The vast majority were lightly wounded, as much of the hospital building had been evacuated in recent days.

Iranian officials insisted that they had not sought to strike the hospital and claimed the attack hit a facility belonging to the Israeli military’s elite technological unit, called C4i. The website for the Gav-Yam Negev advanced technologies park, some 2 miles from the hospital, said C4i had a branch campus in the area.