BIRMINGHAM, Ala. (AP) — With its dozen intensive care beds already full, Cullman Regional Medical Center began looking desperately for options as more and more COVID-19 patients showed up.

Ten beds normally used for less severe cases were transformed into intensive care rooms, with extra IV machines brought in. Video monitors were set up to enable the staff to keep watch over patients whenever a nurse had to scurry away to care for someone else.

The patch did the job — for the time being, at least.

“We’re kind of like a bathtub that’s filling up with water and the drain is blocked,” the hospital’s chief medical officer, Dr. William Smith, said last week.

Alabama, long one of the unhealthiest and most impoverished states in America, has emerged as one of the nation’s most alarming coronavirus hot spots.

Its hospitals are in crisis as the virus rages out of control in a region with high rates of obesity, high blood pressure and other conditions that can make COVID-19 even more dangerous, where access to health care was limited even before the outbreak, and where public resistance to masks and other precautions is stubborn.

The virus has killed more than 335,000 people across the U.S., including over 4,700 in Alabama. Places such as California and Tennessee have also been hit especially hard in recent weeks.

At Cullman Regional, a midsize hospital that serves an agricultural area 55 miles north of Birmingham, the intensive care unit as of last week was at 180% of capacity, the highest in the state. Other hospitals are also struggling to keep up with the crush of people sickened by the virus.

While a typical patient might need ICU treatment for two or three days, Smith said, COVID-19 patients often stay two or three weeks, causing the caseload to build up.

Alabama ranked sixth on the list of states with the most new cases per capita over the past week, according to Johns Hopkins University. Alabama’s latest average positivity rate — the percentage of tests coming back positive for the virus — is almost 40%, one of the highest figures in the country. And the state is seeing an average of 46 deaths per day, up from 30 on Dec. 14

While ICUs nationwide were at 78% capacity during the week of Dec. 18-24, Alabama’s were 91% full, according to the U.S. Health and Human Services Department. As of last week, 15 Alabama hospitals had intensive care units that were at or above capacity, and the ICUs at six more hospitals were at least 96% full.

On Monday, there were 2,800 people in Alabama hospitals with COVID-19, the highest total since the pandemic began.

Experts worry the strain will only increase after the holidays because of new infections linked to travel and gatherings of family and friends.

“I think we are in dire shape. I really do,” said Dr. Don Williamson, head of the Alabama Hospital Association. “I fear our Christmas surge is going to be much worse than the Thanksgiving surge.”

Alabama Gov. Kay Ivey, breaking at the time with some of her Southern counterparts, imposed a statewide mask mandate that has been in place since July, but health officials have struggled to get people to comply. The Republican governor also issued a stay-at-home order early in the pandemic but has staunchly opposed doing so again, saying, “You can’t have a life without a livelihood.”